产品推荐：2-尊龙凯时app

名称：2-(4-(二乙基氨基)-2-甲基苯甲酰)苯甲酸
英文名称：2-(4-(diethylamino)-2-methylbenzoyl)benzoic acid
分子式：c19h21no3

规格：95%

用途：基础原料、有机中间体、医药中间体

合成工艺如下：

the synthesis process is as follows:

sodium hydroxide; sulfuric acid; chlorobenzene; aluminium trichloride

reactants are commercially availlable.
sterling drug inc., us4032527, a1, (1977) a. a mixture of phthalic anhydride (60 g.), n,n-diethyl-m-toluidine (162.8 g.), aluminum chloride (1 20 g.) and chlorobenzene (360 ml.) was heated (75°-95°c.) during one and one-half hours, then dilut ed with water (200 ml., then more). more chlorobenzene (200 ml.) was added and the chlorobenzene layer was separated and steam distilled. addition of sodium hydroxide solution (10percent) to a solutio n of the residue in dilute sulfuric acid (20percent, 250 ml.) afforded 2-(2-methyl-4-(diethylamino)benzoyl)benzoic acid (iv: y2 = ch3, y'4 = (ch3 ch2)2 n, z4 = z"5 = z"6 = z7 = h).