sodium sulfide; water; dmfa;
reactants are commercially availlable.
chen, chixu, wo2011/159839, a2, (2011)  step c: 3-bromopyridine-2-thiola mixture of 3-bromo-2-chloropyridine (0.769g, 4mmol) and sod ium sulfide (0.336g, 6mmol) in dmf (3ml) was heated under microwave irradiation at 130°c for 0.5 hou r. water (50ml) and ethyl acetate (20ml) were added and the layers separated. the aqueous layer was acidified to ph 6 resulting in the formation of a precipitate, which was isolated by filtration and dried under vacuum to yield the product as a yellow solid (0.42g, 55percent).
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