产品推荐：3-尊龙凯时app

规格：97%

外观：黄色固体

用途：基础原料、有机中间体、医药中间体

合成路线如下：

sodium sulfide; water; dmfa;

reactants are commercially availlable.
chen, chixu, wo2011/159839, a2, (2011) [00287] step c: 3-bromopyridine-2-thiola mixture of 3-bromo-2-chloropyridine (0.769g, 4mmol) and sod ium sulfide (0.336g, 6mmol) in dmf (3ml) was heated under microwave irradiation at 130°c for 0.5 hou r. water (50ml) and ethyl acetate (20ml) were added and the layers separated. the aqueous layer was acidified to ph 6 resulting in the formation of a precipitate, which was isolated by filtration and dried under vacuum to yield the product as a yellow solid (0.42g, 55percent).