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hydrogenchloride; ammonium hydroxide; sodium nitrite; sulfuric acid; water; acetic acid;

reactants are commercially availlable.
may and baker limited, us4496390, a1, (1985) (a) 2,3,4,6-tetrafluoroaniline (27.5 g) was diazotised with sodium nitrite (12.5 g) in a mixture of concentrated hydrochloric acid (580 ml) and glacial acetic acid (110 ml). the filtered diazonium sal t solution was reduced by the addition of a solution of stannous chloride dihydrate (108 g) in conce ntrated sulphuric acid (108 ml) at 0°-10°c. the resulting hydrazine hydrochloride solution was evap orated to dryness and the residue was dissolved in water and basified by the addition of aqueous ammonia solution (s.g. 0.880). the precipitated solid was filtered off and the filter pad was well wash ed with diethyl ether. the ethereal washings were combined with ether extracts of the filtrate, dried over sodium sulphate, filtered and evaporated to dryness. trituration of the residue with hexane g ave 2,3,4,6-tetrafluorophenylhydrazine (18.3 g), m .p. 74°-76°c., in the form of off-white crystals.

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