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bischler-mohlau吲哚合成反应亦称bischler吲哚合成反应。从α-卤代芳香酮和过量的苯胺环化生成3-芳基吲哚。

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反应机理

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反应实例


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参考文献


1. möhlau, r. ber. 1881,14, 171–175.

2. bischler, a.; fireman, p. ber.1893, 26, 1346–1349. augustus bischler (1865-1957)

3. sundberg, r. j. thechemistry of indoles; academic press: new york, 1970, pp 164.

4. buu-hoï, n. p.; saint-ruf,g.; deschamps, d.; bigot, p. j. chem. soc. (c) 1971,

2606–2609.

5. houlihan, w. j., ed.; thechemistry of heterocyclic compounds, indoles (part 1),

wiley: new york, 1972.(book).

6. bigot, p.; saint-ruf, g.;buu-hoï, n. p. j. chem. soc., perkin 1 1972, 2573–2576.

7. bancroft, k. c. c.; ward, t.j. j. chem. soc., perkin 1 1974, 1852–1858.

8. coïc, j. p.; saint-ruf, g.;brown, k. j. heterocycl. chem. 1978, 15, 1367–1371.

9. henry, j. r.; dodd, j. h. tetrahedronlett. 1998, 39, 8763–8764.

10. pchalek, k.; jones, a. w.;wekking, m. m. t.; black, d. s. c. tetrahedron 2005, 61,

77–82.

11. sridharan, v.; perumal, s.;avendaño, c.; menéndez, j. c. synlett 2006, 91–95.

12. zhang, j. bischler–möhlauindole synthesis, in name reactions in heterocyclic

chemistry ii; li, j. j., ed.; wiley: hoboken, nj, 2011, pp 84-90.(review).



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