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羧酸与醋酸铅及卤离子(clbri)进行卤代脱羧,产物为少一个碳的卤代烃。这一反应与hunsdiecker反应互补,适用于合成仲或叔氯代烷。


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反应机理


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反应实例


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参考文献


1. kochi, j. k., j. am. chem. soc., 1965, 87, 1811.

2. kochi, j. k., j. am. chem. soc., 1965,87, 2500.

3. kochi, j. k., j. am. chem. soc., 1965, 87, 3609. (d) kochi, j. k., j. org. chem.,1965, 30, 3265.

4. graven, a.; jørgensen, k. a.; dahl, s. and stanczak, a., j. org. chem., 1994, 59, 3543.

5. anderson, j. m. and kochi, j. k., j. am. chem. soc., 1970, 92, 2450.



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